The best time to visit the Red Light District in Amsterdam would be in the evening, as the area is most active during that time. However, it is important to note that the Red Light District can be quite crowded and busy, so it may be best to visit during the week rather than on the weekend. Additionally, it’s important to keep in mind that some of the shops and other businesses in the area may not open until later in the evening, so it might be best to plan your visit for later in the night.